Strategy for virologic response-guided therapy in integrated diagnosis and treatment of hepatitis C in the era of precision medicine in China
10.3969/j.issn.1001-5256.2016.07.008
- VernacularTitle:精准医学时代中国丙型肝炎诊疗一体化的病毒学应答指导治疗策略
- Author:
Huijuan ZHOU
1
;
Qing XIE
Author Information
1. Department of Infectious Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
- Publication Type:Research Article
- Keywords:
hepatitis C;
therapy;
virological response
- From:
Journal of Clinical Hepatology
2016;32(7):1262-1265
- CountryChina
- Language:Chinese
-
Abstract:
At present, long-acting interferon combined with ribavirin is still a major therapeutic method for hepatitis C in China, and precision medicine can help cure more patients with hepatitis C. This article briefly introduces the diagnosis and treatment of hepatitis in China and the importance of the strategy of virologic response-guided therapy (RGT), and analyzes the influencing factors for the achievement of sustained virologic response. HCV RNA quantitation is the foundation of RGT strategy, and HCV RNA quantitation with a high specificity performed at crucial time points during treatment helps to evaluate response accurately, realize the individualized treatment of hepatitis C, and improve the cure rate of hepatitis C.
