Research advances in blocking mother-to-child transmission of hepatitis B virus and hepatitis C virus
10.3969/j.issn.1001-5256.2016.06.045
- VernacularTitle:HBV和HCV母婴传播阻断的研究进展
- Author:
Lengxiao ZHOU
1
;
Tao HAN
Author Information
1. The Third Central Clinical College of Tianjin Medical University, Tianjin 300170, China
- Publication Type:Research Article
- Keywords:
hepatitis B virus;
hepacivirus;
disease transmission, vertical;
review
- From:
Journal of Clinical Hepatology
2016;32(6):1207-1211
- CountryChina
- Language:Chinese
-
Abstract:
Mother-to-child transmission is one of the important routes of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections in China. As for the neonates whose mothers are infected with HBV, a combined injection of hepatitis B vaccine and immunoglobulin is used for vaccination, and about 10% of these neonates may experience a failure. However, as for the neonates whose mothers are infected with HCV, there are no methods for blocking mother-to-child transmission of HCV. This article introduces the development of mother-to-child transmission of HBV and HCV and related mechanisms and influencing factors, as well as the latest advances in methods for blocking, and points out that with further investigations and findings in the field of hepatitis viruses, it may be possible to block mother-to-child transmission of hepatitis viruses.