Direction and progress in research and development of anti-HBV drugs

VernacularTitle:抗HBV药物的研制进展及方向
Author: Xuejun LENG ¹ ; Ying ZHANG ; Jiaochun SHEN
Author Information

1. Department of Infectious Diseases, The Affiliated Hospital of Xuzhou Medical College, Xuzhou, Jiangsu 221002, China
Publication Type:Research Article
Keywords: hepatitis B virus; antiviral agents; review
From: Journal of Clinical Hepatology 2016;32(6):1199-1103
CountryChina
Language:Chinese
Abstract: Chronic hepatitis B (CHB) is considered as the most important risk factor for public health around the world, as well as the main reason for potential diseases to develop into liver cirrhosis and hepatocellular carcinoma. However up to now, there are few methods for the treatment of this lethal viral infection with poor therapeutic effects. At present, we have realized the necessity to develop new drugs. This article reviews the drugs currently available in market or under clinical trials, introduces several drugs with a promising future in each category of anti-HBV drugs, and points out the developmental direction of multi-effect combination of anti-HBV drugs in future, in order to provide the latest advances in HBV treatment for researchers working on HBV and experts engaged in healthcare.