Research advances in MRI features and diagnosis of hepatocellular adenomas
10.3969/j.issn.1001-5256.2016.10.045
- VernacularTitle:各类肝腺瘤磁共振成像特征及诊断的研究进展
- Author:
Jie WU
1
;
Zonglin JING
Author Information
1. Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, China)
- Publication Type:Research Article
- Keywords:
adenoma, liver cell;
magnetic resonance imaging;
diagnosis;
review
- From:
Journal of Clinical Hepatology
2016;32(10):2012-2015
- CountryChina
- Language:Chinese
-
Abstract:
Hepatocellular adenomas (HCA) are rare benign tumors of the liver, and according to the differences in molecular genetics and pathology, HCA is categorized as inflammatory hepatocellular adenoma (IHCA), HCA with hepatocyte nuclear factor 1-alpha mutation (H-HCA), HCA with β-catenin mutation (β-HCA), and an undefined type. The incidence of these four types is 40%-50%, 30%-40%, 10%-15%, and 10%, respectively. In these four types of HCA, β-HCA has high risk of bleeding and malignant transformation, while H-HCA is not likely to show malignant transformation. Therefore, the accurate diagnosis of these types of HCA is very important. This article introduces the radiological features of these types of HCA on conventional MRI and hepatocyte-targeted contrast-enhanced scan and compares these findings with other types of liver solid tumors such as focal nodular hyperplasia, nodular regenerative hyperplasia, liver cancer in non-cirrhotic patients, and fibrolamellar carcinoma of the liver. It is pointed out that MRI and hepatocyte-targeted contrast agents play an important role in the diagnosis and differentiation of HCA.
