Research advances in immunotherapy for chronic hepatitis B
10.3969/j.issn.1001-5256.2016.10.038
- VernacularTitle:慢性乙型肝炎免疫治疗进展
- Author:
Lilin TAO
1
;
Xi LI
;
Jia WEI
Author Information
1. Department of Gastroenterology, The Fourth Affiliated Hospital of Kunming Medical University, Kunming 650021, China)
- Publication Type:Research Article
- Keywords:
hepatitis B, chronic;
immunotherapy;
review
- From:
Journal of Clinical Hepatology
2016;32(10):1984-1988
- CountryChina
- Language:Chinese
-
Abstract:
At present, nucleos(t)ide analogues and interferon-α still have limited effects in patients with chronic hepatitis B (CHB), and therefore, it is of vital importance to develop more effective therapeutic strategies to improve the treatment outcome of CHB patients. This article introduces the immunotherapy for CHB, including therapeutic vaccines (protein vaccines, DNA vaccines, and dendritic cell vaccines) and cell regulation therapy, and points out that immunotherapy is considered a promising treatment regimen for HBV infection. With further studies on the clinical outcome after HBV infection, significant advances have been achieved in immunotherapy for CHB.
