Advances in immunological treatment of autoimmune hepatitis
10.3969/j.issn.1001-5256.2016.10.010
- VernacularTitle:自身免疫性肝炎免疫学治疗进展
- Author:
Jun ZHANG
1
;
Qixia WANG
;
Xiong MA
Author Information
1. Department of Gastroenterology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Digestive Disease, Shanghai 200001, China)
- Publication Type:Research Article
- Keywords:
hepatitis, autoimmune;
immunology;
therapy
- From:
Journal of Clinical Hepatology
2016;32(10):1874-
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, autoimmune hepatitis (AIH) has attracted more and more attention due to its unique clinicopathological features. However, its incidence and clinical features remain unclear, and systematic and in-depth studies are still needed. This article reviews the epidemiology, etiology, pathogenesis, clinical features, and diagnosis and treatment of AIH and points out that clinical studies or animal models of AIH have proved the effects of TNF-α neutralizing antibody, rituximab, all-trans retinoic acid, and regulatory T cell transplantation in the treatment of AIH.
