Innate immune response and acquired immune response in patients with chronic HBV infection
10.3969/j.issn.1001-5256.2016.10.008
- VernacularTitle:慢性HBV感染的天然免疫与获得性免疫应答
- Author:
Qin WANG
1
;
Jia LIU
;
Dongliang YANG
Author Information
1. Department of Infectious Diseases, Union Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430022, China
- Publication Type:Research Article
- Keywords:
hepatitis B virus;
immunity, active;
immunization, passive
- From:
Journal of Clinical Hepatology
2016;32(10):1863-1869
- CountryChina
- Language:Chinese
-
Abstract:
After the infection with HBV, the host′s antiviral immune response is a key factor for the outcome of infection. At present, it is widely believed that the host′s innate immunity and acquired immunity are impaired during chronic HBV infection, because of which HBV clearance cannot be achieved. To achieve a long-lasting immune control of HBV infection, we need to comprehensively understand the mechanisms of dysfunction of innate immune response and specific immune response in chronic HBV infection. This article summarizes the research advances in the immune response mechanism of chronicity of HBV infection.
