Features of immune response during antiviral therapy in patients with chronic hepatitis B
10.3969/j.issn.1001-5256.2016.10.007
- VernacularTitle:慢性乙型肝炎患者抗病毒治疗过程中的免疫应答特点
- Author:
Weibin WANG
1
;
Yongyin LI
;
Jinlin HOU
Author Information
1. State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of Viral Hepatitis Research, Department of Infectious Diseases and Hepatology Unit, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
- Publication Type:Research Article
- Keywords:
hepatitis B, chronic;
antiviral agents;
immunity
- From:
Journal of Clinical Hepatology
2016;32(10):1858-1862
- CountryChina
- Language:Chinese
-
Abstract:
Host immune response is a double-edged sword and participates in liver injury and viral control in patients with HBV infection. Antiviral therapy with nucleos(t)ide analogues and interferon may improve prognosis through regulating host immune response. This article describes the role of host immune response in chronic HBV infection and its features during antiviral therapy and emphasizes the importance of host immune reconstruction in sustained control of HBV infection.