Research advances in diagnosis and treatment of IgG4-associated autoimmune hepatitis
10.3969/j.issn.1001-5256.2016.09.042
- VernacularTitle:IgG4相关自身免疫性肝炎诊治的研究进展
- Author:
Xiaodong SHI
1
;
Qi WEI
;
Min YU
Author Information
1. Department of Rheumatology, The First Hospital of Jilin University, Changchun 130021, China
- Publication Type:Research Article
- Keywords:
hepatitis, autoimmune;
immunoglobulin G;
diagnosis;
therapy;
review
- From:
Journal of Clinical Hepatology
2016;32(9):1819-1821
- CountryChina
- Language:Chinese
-
Abstract:
Autoimmune hepatitis (AIH) is a chronic progressive inflammatory disease involving the liver parenchyma. In recent years, there have been more studies focusing on IgG4-associated diseases. Foreign scholars have found that patients with AIH also have IgG4-positive plasma cell infiltration in the liver, suggesting that IgG4 may be involved in the pathogenesis of AIH, and this disease is considered a special type of AIH and thus it is called IgG4-associated AIH (IgG4-AIH). This article reviews the research advances in the diagnosis and treatment of AIH and IgG4-AIH, so as to enhance clinical doctors′knowledge of such diseases.