The role of MAPK signaling pathway in development/progression and treatment of liver cancer
10.3969/j.issn.1001-5256.2016.09.040
- VernacularTitle:MAPK信号通路在肝癌发生发展及治疗中的作用
- Author:
Wangjiu CIDAN
1
;
Kun LIN
;
Zaiming LU
Author Information
1. Department of Radiology, Shengjing Hospital of China Medical University, Shenyang 110004, China
- Publication Type:Research Article
- Keywords:
liver neoplasms;
mitogen-activated protein kinases;
MAP kinase signaling system;
review
- From:
Journal of Clinical Hepatology
2016;32(9):1810-1813
- CountryChina
- Language:Chinese
-
Abstract:
Abnormal activation of the mitogen-activated protein kinase (MAPK) signaling pathway is closely associated with the development, progression, and metastasis of liver cancer. This article introduces the expression of MAPK proteins in liver cancer and its role in the proliferation, differentiation, and metastasis of liver cancer, and elaborates on the value of the MAPK signaling pathway in the treatment and prognostic evaluation of liver cancer. It is pointed out that the MAPK signaling pathway plays an important role in the development/progression and treatment of liver cancer and is a potential molecular target for the treatment and prognostic evaluation of liver cancer.
