Advances in diagnosis and treatment of patients with acute-on-chronic liver failure complicated by acute kidney injury
10.3969/j.issn.1001-5256.2016.09.011
- VernacularTitle:慢加急性肝衰竭并发急性肾损伤的诊治进展
- Author:
Xiaopeng LI
1
;
Zhenping WU
;
Lunli ZHANG
Author Information
1. Department of Infectious Diseases & Key Laboratory of Liver Regenerative Medicine of Jiangxi Province, The First Affiliated Hospital of Nanchang University, Nanchang 330006, China
- Publication Type:Research Article
- Keywords:
liver failure;
renal insufficiency, acute;
diagnosis;
therapy
- From:
Journal of Clinical Hepatology
2016;32(9):1688-1693
- CountryChina
- Language:Chinese
-
Abstract:
Acute-on-chronic liver failure (ACLF) is the most common type of liver failure in China, and it has complicated clinical manifestations and high mortality. When the patients experience ACLF complicated by acute kidney injury (AKI), they tend to have a prolonged length of hospital stay and a high risk of multiple organ failure, which always suggests poor prognosis. This article briefly describes the advances in the definition, causative factors, prognostic evaluation, diagnostic markers, and treatment of ACLF complicated by AKI. It is pointed out that early identification, diagnosis, and intervention of AKI helps to reverse kidney injury and avoid the development of severe AKI.
