Disease assessment and prognosis of liver failure
10.3969/j.issn.1001-5256.2016.09.008
- VernacularTitle:肝衰竭的病情评估及预后判断
- Author:
Jing ZHANG
1
;
Xinmin ZHOU
Author Information
1. Department of Gastroenterology, Xijing Hospital of Fourth Military Medical University, Xi′an 710032, China
- Publication Type:Research Article
- Keywords:
liver failure;
liver transplantation;
prognosis;
scoring system
- From:
Journal of Clinical Hepatology
2016;32(9):1673-1677
- CountryChina
- Language:Chinese
-
Abstract:
Liver failure has a high fatality rate and greatly threatens human health. Liver transplantation can effectively reduce the fatality rate. However, the problems such as donor shortage and allograft rejection limit the wide application of liver transplantation. An accurate early assessment helps to evaluate patients′ condition and optimize therapeutic strategies. At present, commonly used systems for prognostic evaluation include the King′s College Hospital, MELD, integrated MELD, Child-Pugh score, CLIF-SOFA, CLIF-C ACLFS, and D-MELD, and each system has its own advantages and disadvantages. Among these systems, the MELD scoring system is the most commonly used one, and the D-MELD scoring system is the most innovative one, which can be used for patients on the waiting list for liver transplantation. This article elaborates on the characteristics and predictive value of each scoring system in clinical practice.
