Expression and role of heat shock protein 70 in hepatocellular carcinoma
10.3969/j.issn.1001-5256.2016.11.047
- VernacularTitle:热休克蛋白70在肝细胞癌中的表达及作用
- Author:
Zeling HE
1
;
Jianbiao CAO
;
Gongren FAN
Author Information
1. The Second Clinical Medical School, Shanxi Medical University, Taiyuan 030001, China
- Publication Type:Research Article
- Keywords:
carcinoma, hepatocellular;
HSP70 heat-shock proteins;
review
- From:
Journal of Clinical Hepatology
2016;32(11):2206-2209
- CountryChina
- Language:Chinese
-
Abstract:
Heat shock protein 70 (HSP70) is expressed differently in hepatocellular carcinoma (HCC) tissues. Since its expression and regulatory mechanism remain unclear, whether HSP70 can help with the early diagnosis, treatment, and prognostic evaluation of HCC has become a hot research topic. This article reviews the source of HSP70 and its family, abnormal expression of HSP70 in HCC, and its association with treatment methods and prognostic evaluation of HCC, in order to provide a reference for clinical diagnosis and treatment of HCC.