Current status of research on microRNA associated with colorectal cancer liver metastasis
10.3969/j.issn.1001-5256.2016.12.034
- VernacularTitle:结直肠癌肝转移相关microRNA的研究现状
- Author:
Dongxu WANG
1
;
Tingting HUO
;
Yaowen TIAN
Author Information
1. School of Medicine and life Sciences, Jinan University-Shandong Academy of Medical Sciences, Jinan 250000, China)
- Publication Type:Research Article
- Keywords:
colorectal neoplasms;
neoplasm metastasis;
microRNAs;
review
- From:
Journal of Clinical Hepatology
2016;32(12):2387-2390
- CountryChina
- Language:Chinese
-
Abstract:
Tumor metastasis is a complicated process with multiple steps, and liver metastasis is the most common metastatic mode of colorectal cancer. Deep understanding and study of metastatic mechanism helps to find solutions for colorectal cancer liver metastasis. Recent studies have shown that microRNA are involved in tumor metastasis and recurrence, and studies on microRNA associated with colorectal cancer liver metastasis can provide new thoughts for the development and progression, diagnosis and treatment, and prognosis of the disease. This article summarizes the research advances in microRNA associated with colorectal cancer liver metastasis and reviews the biological function and molecular mechanism of microRNA, which suggests that microRNA have a vital significance in the field of tumor metastasis, especially colorectal cancer liver metastasis.
