Effect of splenectomy on liver cirrhosis and related surgical issues
10.3969/j.issn.1001-5256.2016.12.033
- VernacularTitle:脾切除术对肝硬化的影响及手术相关问题的探讨
- Author:
Degang KONG
1
;
Shichun LU
Author Information
1. Department of Hepatopancreatobiliary Surgery, The Second Affiliated Hospital of Tianjin Medical University, Tianjin 300211, China
- Publication Type:Research Article
- Keywords:
splenectomy;
liver cirrhosis;
hypertension， portal;
surgical procedures， operative;
review
- From:
Journal of Clinical Hepatology
2016;32(12):2383-2386
- CountryChina
- Language:Chinese
-
Abstract:
Patients with liver fibrosis and cirrhosis experience certain changes in spleen morphology and function, and there is always a controversy over whether to perform splenectomy in patients with liver cirrhosis. As a surgical treatment of recurrent portal hypertension complicated by esophagogastric variceal bleeding, splenectomy can reduce portal venous pressure, reduce the possibility of gastrointestinal bleeding, and correct the reduced white blood cell count and platelet count. It can also protect the liver by improving liver function, promoting regeneration of hepatocytes, and inhibiting the progression of liver fibrosis. With reference to available clinical and laboratory data, this article reviews the effect of splenectomy on the cirrhotic liver and related issues such as selection of surgical procedures and prevention and treatment of postoperative complications, in order to promote splenectomy in patients with liver cirrhosis.
