Application of immune induction therapy with antibodies in liver transplantation
10.3969/j.issn.1001-5256.2015.12.010
- VernacularTitle:抗体免疫诱导治疗在肝移植中的应用
- Author:
Yang YANG
1
;
Yinan DENG
Author Information
1. Center for Liver Transplantation, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510630, China
- Publication Type:Research Article
- Keywords:
liver transplantation;
immunity induction;
therapy
- From:
Journal of Clinical Hepatology
2015;31(12):2031-2034
- CountryChina
- Language:Chinese
-
Abstract:
Immune induction therapy with antibodies has been widely applied in liver transplantation. This paper introduces common antibodies for immune induction and their application in liver transplantation, and points out that immune induction therapy with antibodies reduces the dosage of hormones and calcineurin inhibitors (cyclosporine and tacrolimus), reduces infections effectively, protects renal function, prevents acute rejection reaction, and finally improves the prognosis of transplant recipients. The effect of immune induction therapy with antibodies on hepatitis and liver cancer still needs further investigation.Key words：liver transplantation；immunity induction；therapy
