Research advances in non-invasive diagnosis models for liver fibrosis in chronic hepatitis B

VernacularTitle:慢性乙型肝炎肝纤维化无创性诊断模型的研究进展
Author: Qingrong TANG ¹ ; Qing HE ; Qiyuan TANG
Author Information

1. The Third Hospital of Shenzhen, Shenzhen, Guangdong 518112, China
Publication Type:Research Article
Keywords: hepatitis B, chronic; liver cirrhosis; proportional hazards models; review
From: Journal of Clinical Hepatology 2015;31(8):1355-1359
CountryChina
Language:Chinese
Abstract: It is vital for reducing the occurrence of complications, such as liver cirrhosis and hepatic carcinoma, to early diagnose liver fibrosis in chronic hepatitis B and intervene in time with antiviral therapy. Although liver biopsy is the "golden standard" for the diagnosis of fibrosis, it has certain disadvantages, such as complicated operation, invasion, and occurrence of complications. Therefore, non-invasive diagnosis models have gained more and more attention clinically. In this review, we summarizes the non-invasive diagnosis models for chronic hepatitis B that have been established throughout the world. It is noticed that there are a number of models being studied and each model has a diagnostic value, to some degree, but a lack of consensus exists. The development of more efficient models that can replace liver biopsy still needs further research to assess liver fibrosis in chronic hepatitis B and guide antiviral therapy.