Recent research on association between gene polymorphisms of IL-28B and other cytokines and HCV infection

VernacularTitle:白细胞介素28B等细胞因子基因多态性与HCV感染的关系
Author: Yijia MAO ¹ ; Xiaorong MAO ; Ni JIANG
Author Information

1. Medical Department, The First Hospital of Lanzhou University, Lanzhou 730000, China
Publication Type:Research Article
Keywords: hepacivirus; interleukins; cytokines; polymorphism single nudeotide; review
From: Journal of Clinical Hepatology 2015;31(8):1347-1350
CountryChina
Language:Chinese
Abstract: It has been confirmed that the body′s response to hepatitis C virus (HCV) is not only associated with virus, but also associated with some cytokines and their gene polymorphisms. In this paper, the current research on some cytokines associated with HCV and their gene polymorphisms is reviewed. And it is shown that interleukin-28B is closely associated with the course and prognosis of chronic hepatitis C (CHC). Therefore, it is of great significance for the clinical diagnosis and treatment of CHC to investigate host cytokines and their gene polymorphisms.