Discussion on idiosyncratic drug-induced liver injury in children
10.3969/j.issn.1001-5256.2015.08.008
- VernacularTitle:浅谈儿童特异质性药物性肝损伤
- Author:
Yi LU
1
;
Hui YU
Author Information
1. Liver Research Center, Children′s Hospital of Fudan University, Shanghai 201102, China)
- Publication Type:Research Article
- Keywords:
drug-induced liver injury;
diagnosis;
therapy;
child
- From:
Journal of Clinical Hepatology
2015;31(8):1215-1217
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, the incidence of idiosyncratic drug-induced liver injury (IDILI) has been increasing, posing a threat to human health. This article reviews the incidence, pathogenesis, and the principles of clinical diagnosis and treatment of IDILI. Because there is limited literature on IDILI in children, so this article simply describes the experience in the diagnosis and treatment of IDILI in children. It is considered that to reduce the incidence of IDILI in children, drug indications should be strictly followed, and molecular test and accurate medical treatment should be promoted.
