Investigation of impairment of liver function in local residents of Miaofeng Village, Wushan County, China
10.3969/j.issn.1001-5256.2015.06.030
- VernacularTitle:武山县苗丰村居民肝损害情况横断面调查分析
- Author:
Zhongxia YANG
1
;
Xiaorong MAO
;
Hong YUAN
Author Information
1. The First Hospital of Lanzhou University, Lanzhou 730000, China
- Publication Type:Research Article
- Keywords:
hepoctic insufficiency;
environmental monitoring;
Gansu
- From:
Journal of Clinical Hepatology
2015;31(6):955-
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo assess the impairment of liver function and investigate possible causes in local residents in Miaofeng Village, Mali Town, Wushan County, Gansu Province, China, and to provide a basis for the etiological study of idiopathic liver damage. MethodsThe residents in Miaofeng Village were screened for liver function and an epidemiological study was conducted. Serological testing was performed for those with abnormal screening results. Trace elements in drinking water and soil such as arsenic, chromium, and selenium were also tested. ResultsOf all residents, 23.8% and 10.7% showed abnormal levels of alanine aminotransferase and aspartate aminotransferase, respectively. Positivity of HBsAg was detected in 11 cases, fatty liver was identified in 3 cases, and absence of selenium in soil was also confirmed. ConclusionA proportion of local residents in Miaofeng Village have impaired liver function and the absence of selenium in soil may be a contributing factor to this phenomenon.
