Research advances in targeted therapy for hepatocellular carcinoma
10.3969/j.issn.1001-5256.2019.11.041
- VernacularTitle:肝细胞癌的靶向治疗
- Author:
Shen HUANG
1
;
Chenglei YANG
;
Zhiming ZHANG
Author Information
1. Department of Hepatobiliary Surgery, The Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China
- Publication Type:Research Article
- Keywords:
carcinoma, hepatocellular;
molecular targeted therapy;
therapeutics
- From:
Journal of Clinical Hepatology
2019;35(11):2573-2577
- CountryChina
- Language:Chinese
-
Abstract:
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors. Due to the insidious onset, poor prognosis, and lack of specificity of HCC, most patients have reached the advanced stage at the time of diagnosis. Conventional treatment methods, such as surgical resection, liver transplantation, radiotherapy, and chemotherapy, have limited therapeutic effects and fail to bring significant benefits to patients. With the improvement of science and technology and medical level in recent years, targeted therapy drugs have gradually entered people’s vision due to the breakthroughs in the treatment of HCC and thus bring new hope to patients with advanced HCC. Targeted drugs have attracted wide attention due to good molecular selectivity, targeted killing of tumor cells, and protection of normal tissue. This article reviews the research advances in targeted therapy for HCC.