Vertical transmission of hepatitis B virus: Modes and blocking strategies
10.3969/j.issn.1001-5256.2019.11.037
- VernacularTitle:HBV垂直传播形式及阻断策略
- Author:
Fei ZHAO
1
;
Fei LIU
;
Zhongfeng WANG
Author Information
1. Department of Obstetrics, The First Hospital of Jilin University, Changchun 130061, China
- Publication Type:Research Article
- Keywords:
hepatitis B virus;
infectious disease transmission, vertical;
antiviral agents
- From:
Journal of Clinical Hepatology
2019;35(11):2557-2560
- CountryChina
- Language:Chinese
-
Abstract:
Mother-to-child vertical transmission is the main mode of transmission of chronic hepatitis B in China. The probability of failure in blocking vertical transmission is about 10% in pregnant mothers with a high viral load, and therefore, correct management of hepatitis B virus (HBV) is of great importance during pregnancy. In addition, viral treatment during pregnancy should take into account the risk of vertical transmission, the health of pregnant women, and the safety of fetus, and each treatment method or prevention option needs to be carefully evaluated. Reasonable antiviral methods, drug selection, and drug withdrawal time can reduce the probability of mother-to-child transmission. This article summarizes the modes of mother-to-child vertical transmission of chronic hepatitis B and related blocking strategies, so as to provide a reference for improving the blocking rate of vertical transmission of HBV.
