Research status of the relationship between periodontitis and systemic disease
10.12016/j.issn.2096-1456.2018.09.012
- Author:
CHENG Miaoying
1
;
LIANG Dan
1
;
TANG Zhiqun
1
;
WU Hongkun
1
Author Information
1. State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Dept. of Geriatric Dentistry,West China Hospital of Stomatology, Sichuan University
- Publication Type:Review
- Keywords:
Periodontitis;
Systemic disease;
Inflammatory factors;
Cardiovascular disease;
Atherosclerosis;
Type 2 diabetes;
Chronic obstructive pulmonary disease;
Inflammation
- From:
Journal of Prevention and Treatment for Stomatological Diseases
2018;26(9):606-612
- CountryChina
- Language:Chinese
-
Abstract:
Periodontitis is a common infectious disease that is harmful to human oral health and is the main cause of tooth loss. Periodontal inflammation can damage the integrity of the epithelium, causing periodontal pathogens to spread to the systemic circulation, and the periodontal pocket contains a large number of inflammatory mediators, especially those related to chronic inflammation, such as tumor necrosis factor-α, interleukins and prostaglandins, which will enter the blood circulation system from periodontal pocket and cause systemic inflammatory response. Periodontitis is closely related to the occurrence and development of systemic diseases, including cardiovascular, endocrine, respiratory, immune, and nervous systems. Inflammatory responses and inflammatory factors may be the mechanism of the association between periodontitis and multiple systemic diseases. This article reviews the current research on the relationship between periodontitis and systemic disease.
- Full text:牙周炎与全身系统性疾病关系的研究现状.pdf
