Osteogenic potential of recombinant human bone morphogenetic protein-2 combined with Bio-oss bone substitute in implant restorations in anterior esthetic region
10.12016/j.issn.2096-1456.2018.09.008
- Author:
LI Xueqian
1
,
2
;
ZHANG Qiao
3
;
ZHANG Xiaoxin
1
,
2
;
ZHANG Yufeng
1
,
2
Author Information
1. School &
2. Hospital of Stomatology, Wuhan University
3. The Affiliated Stomatology Hospital, College of Medicine, Zhejiang University
- Publication Type:Journal Article
- Keywords:
Dental implant;
Anterior tooth area;
Bone defect;
Osteogenesis;
rhBMP-2;
Bio-oss bone substitute
- From:
Journal of Prevention and Treatment for Stomatological Diseases
2018;26(9):584-591
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the osteogenic potential of recombinant human bone morphogenetic protein 2 (rhBMP-2) combined with Bio-oss bone substitute in the implant restoration of bone defects in the anterior esthetic region.
Methods: Twelve patients who underwent the immediate placement of 20 implants with a bone augmentation procedure using rhBMP-2 and Bio-oss were included in this study. Changes in the height and thickness of the buccal bone over 6 months were measured, and the soft tissue was evaluated using the pink esthetic score (PES) after crown placement.
Results: All 20 implants were successfully osseointegrated, and the average increase in bone height was 1.9 mm; different degrees of bone height growth were observed for 17 (85%) implants sites. In one case, there was a severe bone fracture on the buccal side before the operation, resulting in bone plate resorption and decreased alveolar bone height. The bone height did not change significantly in 2 cases. The thickness of the buccal bone plate for all implants was greater than 1 mm. The average thickness was 1.9 mm, and the average PES was 9.8 points.
Conclusion: rhBMP-2 combined with Bio-oss bone substitute has a preferable effect on the restoration of bone defects in the anterior esthetic area, and can achieve good aesthetic effect.
- Full text:rhBMP-2联合Bio-oss骨粉在前牙美学区种植中的成骨效果.pdf
