Phenolic constituents from Wikstroemia chamaedaphne.
10.19540/j.cnki.cjcmm.2019.0017
- Author:
Xue LIANG
1
;
Ying-Ying JIAO
1
;
Wen-Hao WANG
1
;
Shi-Fei LI
2
;
Li-Wei ZHANG
2
Author Information
1. Key Laboratory of Chemical Biology and Molecular Engineering of Education Ministry,Institute of Molecular Science,Shanxi University Taiyuan 030006,China Modern Research Center for Traditional Chinese Medicine,Shanxi University Taiyuan 030006,China.
2. Key Laboratory of Chemical Biology and Molecular Engineering of Education Ministry,Institute of Molecular Science,Shanxi University Taiyuan 030006,China.
- Publication Type:Journal Article
- Keywords:
Wikstroemia chamaedaphne;
flavonoids;
lignanoids;
phenolic constituents
- MeSH:
Chromatography, High Pressure Liquid;
Flavonoids;
analysis;
Molecular Structure;
Phenols;
analysis;
Phytochemicals;
analysis;
Wikstroemia;
chemistry
- From:
China Journal of Chinese Materia Medica
2019;44(5):962-967
- CountryChina
- Language:Chinese
-
Abstract:
The phenolic constituents of Wikstroemia chamaedaphne were investigated by various column chromatographic methods including silica gel,Sephadex LH-20,ODS and preparative HPLC,and their chemical structures were identified by physico-chemical properties and spectral analyses. Thirteen phenolic compounds were isolated and elucidated,including five flavonoids: luteolin 7-O-β-D-glucopyranoside(1),luteolin 4'-O-β-D-glucopyranoside(2),kaempferol 3-O-β-D-glucopyranoside(3),chrysoeriol 4'-O-β-D-glucopyranoside(4),chrysoeriol(5); and eight lignans:(-)-secoisolariciresinol(6),acanthosessilin A(7),(-)-nortrachelogenin(8),(+)-isolariciresinol(9),sesamin(10),syringaresinol(11),(+)-epipinoresinol(12),and [3,3',4,4'-tetrahydro-6,6'-dimethoxy-3,3'-bi-2 H-benzopyran]-4,4'-diol(13). Compounds 1, 3, 5-8, 10, 11 and 13 were obtained from the plants of W. chamaedaphne for the first time,and compounds 1,5,7,10 and 13 were obtained from the Wikstroemia genus for the first time.