Evaluation of scavenging activity of hydrogen peroxide in different origins of Liropes Radix by HPLC-UV-CL system.
10.19540/j.cnki.cjcmm.20181228.001
- Author:
Fei-Leng CHEN
1
;
Zheng-Fang HU
1
;
Jin QI
1
Author Information
1. Key Laboratory of Traditional Chinese Medicine Evaluation and Translational Research,China Pharmaceutical University Nanjing 211198,China.
- Publication Type:Journal Article
- Keywords:
HPLC-UV-CL;
Liropes Radix;
hydrogen peroxide
- MeSH:
Chromatography, High Pressure Liquid;
Drugs, Chinese Herbal;
Free Radical Scavengers;
chemistry;
Hydrogen Peroxide;
isolation & purification;
Liriope Plant;
chemistry;
Phytochemicals;
chemistry;
Plant Extracts;
chemistry;
Plant Roots;
chemistry
- From:
China Journal of Chinese Materia Medica
2019;44(5):990-995
- CountryChina
- Language:Chinese
-
Abstract:
The hydrogen peroxide generation system was used to analyze the scavenging activity of hydrogen peroxide by Liropes Radix from different origins by HPLC-UV-CL. The UV-CL fingerprints of Liropes Radix from different origins were evaluated,and the HPLC-UV and LC-CL fingerprints were systematically analyzed and evaluated. The results showed that the ether fractions of Liriope spicata var. prolifera and L. muscari had good scavenging activity of hydrogen peroxide,and the total activity of different origins varied greatly,while the similar samples had similar activities. The total antioxidant activity of L. muscari is higher than that of L. spicata var.prolifera. The similarity analysis of the two fingerprints was carried out by two different analytical methods. The chemical fingerprints and the active fingerprints have different characteristics. The contribution of each fingerprint to the total peak area and total activity is also different. There are significant differences between the two different fingerprint clustering results.
