Determination of forbidden and restricted pesticides in Angelicae Sinensis Radix.
10.19540/j.cnki.cjcmm.20181121.002
- Author:
An-Ping LI
1
;
Zhi-Rong LIU
1
;
Ping-Rong YANG
1
;
Hong-Yu JIN
2
Author Information
1. Institutes for Food and Drug Control of Gansu Province Langzhou 730000,China.
2. National Institutes for Food and Drug Control Beijing 100050,China.
- Publication Type:Journal Article
- Keywords:
Angelicae Sinensis Radix;
forbidden and restricted pesticides;
liquid chromatography tandem mass spectrometry;
multi-pesticides residue;
risk management
- MeSH:
Chromatography, Liquid;
Pesticide Residues;
Pesticides;
chemistry;
Tandem Mass Spectrometry
- From:
China Journal of Chinese Materia Medica
2019;44(4):750-757
- CountryChina
- Language:Chinese
-
Abstract:
The present study is to establish a method for simultaneous determination of 50 kinds of pesticides in Angelicae Sinensis Radix by using liquid chromatography tandem mass spectrometry. The forbidden,restricted and customary pesticides were picked out as detecting indexes according to the principals of risk management. The factors affecting the extraction,purification,and detection were optimized,and the final condition was established as follows: the samples were extracted with acetonitrile. The separation of target compounds were performed by liquid column,and quantitative analysis was carried out by LC-MS/MS with MRM model. The calibration curves were linear in the range of 1-100 μg·L~(-1) with correction coefficients of greater than 0. 990. The recoveries of more than 93. 9%pesticides were ranged from 60% to 140% at three spiked levels. The detecting indexes in the method cover most forbidden and restricted pesticides,which is meaningful for the safety supervision of the Angelicae Sinensis Radix. With the advantage of rapidness and accuracy,this method can be used for routine determination of multi-pesticides in Angelicae Sinensis Radix.
