Research progress on pathogenesis of ischemic stroke and traditional Chinese medicine commonly used for treatment of ischemic stroke.
10.19540/j.cnki.cjcmm.20180921.002
- Author:
Jing-Bo ZHU
1
;
Yong-Hua WANG
1
;
Zhong-Dong HU
2
;
Jun LI
2
Author Information
1. Jiangsu Kanion Pharmaceutical Co., Ltd. Lianyungang 222001, China.
2. Modern Research Center for Traditional Chinese Medicine, School of Chinese Materia Medica, Beijing University of Chinese Medicine Beijing 100029, China.
- Publication Type:Journal Article
- Keywords:
ischemic stroke;
pathogenesis;
research progress;
traditional Chinese medicine
- MeSH:
Brain Ischemia;
physiopathology;
therapy;
Humans;
Medicine, Chinese Traditional;
Research;
Stroke;
physiopathology;
therapy
- From:
China Journal of Chinese Materia Medica
2019;44(3):422-432
- CountryChina
- Language:Chinese
-
Abstract:
Stroke has become the second leading cause of death in the world, and the most common type is the ischemic stroke. Due to its rapid onset and complex conditions, ischemic stroke is a major neurological disorder that causes disability. Ischemic stroke mainly results from atherosclerosis, and the pathogenesis of ischemic stroke mainly includes energy metabolism disorders in the brain, the toxicity of excitatory amino acids, oxidative/nitrification stress, inflammatory response, apoptosis, and autophagy. With the characteristics of multi-component and multi-target, traditional Chinese medicine could be used to treat ischemic stroke at different stages. This article summarized the latest research progress on the pathogenesis of ischemic stroke and commonly used traditional Chinese medicine for treatment of ischemic stroke in order to provide references for the further research and clinical treatment of ischemic stroke.
