Chemical constituent analysis for seeds of Celosia argentea by UPLC-ESI-Q-TOF-MS.
10.19540/j.cnki.cjcmm.20181126.001
- Author:
Sheng LIU
1
;
Xin WANG
2
;
Jin-di XU
1
;
Pan-Pan CHEN
2
;
Qian-Yue ZHANG
2
;
Ming-Zhong WANG
3
;
Jian-Ming JU
1
;
Jun-Ting FAN
2
Author Information
1. Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine Nanjing 210028, China Jiangsu Province Academy of Traditional Chinese Medicine Nanjing 210028, China.
2. School of Pharmacy, Nanjing Medical University Nanjing 211166, China.
3. Shenzhen Kivita Innovative Drug Discovery Institute Shenzhen 518057, China.
- Publication Type:Journal Article
- Keywords:
Celosia argentea seeds;
UPLC-ESI-Q-TOF-MS;
chemical constituents;
cyclic peptides;
flavonoids;
triterpenoids
- MeSH:
Celosia;
chemistry;
Chromatography, High Pressure Liquid;
Phytochemicals;
analysis;
Seeds;
chemistry;
Spectrometry, Mass, Electrospray Ionization
- From:
China Journal of Chinese Materia Medica
2019;44(3):500-508
- CountryChina
- Language:Chinese
-
Abstract:
This Paper aimed to analyze and identify the chemical constituents from the seeds of Celosia argentea by UPLC-ESI-Q-TOF-MS. The analysis was performed on an ACQUITY HSS T3 reverse phase column(2.1 mm ×100 mm, 1.8 μm). The mobile phase consisting of 0.1% formic acid acetonitrile and 0.1% aqueous formic acid was used for gradient elution, and the flow rate was 0.4 mL·min~(-1). Mass spectrometry was applied for the qualitative analysis under positive and negative ionization modes and ESI ion source. Data was analyzed by Masslynx 4.1 software, literatures in SciFinder database, and standards. A total of 49 compounds, including 14 triterpenoids, 17 flavonoids, 11 cyclic peptides, 2 phenols, 2 organic acids, and 3 steroids were putatively identified. Among them, 19 compounds were firstly reported from this species. In-depth chemical constituent analysis for the seeds of C. argentea were accomplished here, and the findings could lay a good foundation for its quality control and clarifying the material basis of its efficacy.
