Nature-effect relationship research of traditional Chinese medicine for promoting blood circulation and removing blood stasis based on nature combination.
10.19540/j.cnki.cjcmm.20180913.001
- Author:
Dong-Xue WU
1
;
Meng-Qi HUO
1
;
Ning HOU
1
;
Jing LI
1
;
Min LIU
1
;
Yan-Ling ZHANG
1
;
Yan-Jiang QIAO
1
Author Information
1. State Administration of Traditional Chinese Medicine,Research Center of Traditional Chinese Medicine-Information Engineering,Beijing University of Chinese Medicine Beijing 100102,China.
- Publication Type:Journal Article
- Keywords:
nature combination;
nature-effect relationship;
promoting blood circulation and removing blood stasis;
protein interaction network;
warm-pungent-liver
- MeSH:
Blood Circulation;
Blood Coagulation;
Humans;
Inflammation;
Lipid Metabolism;
Liver;
Medicine, Chinese Traditional
- From:
China Journal of Chinese Materia Medica
2019;44(2):205-211
- CountryChina
- Language:Chinese
-
Abstract:
The efficacy of traditional Chinese medicine is the therapeutic effect of the drug on the body. The nature of traditional Chinese medicine is a further generalization of the effect of efficacy,and there is an intrinsic relationship between efficacy and nature of traditional Chinese medicine. In this study,the nature-effect relationship is found on the whole level,through the research mode of " nature combination-targets of traditional Chinese medicine-modules of protein interaction network-efficiency". The results showed that the warm-pungent-liver protein interaction network mainly participated in lipid catabolic process,blood coagulation,platelet activation,heme oxidation,platelet degranulation,apoptotic process,acute inflammatory response to exert the effect of anti-tumor,antithrombotic,anti-myocardial ischemia and anti-inflammatory.
