Chemical Composition of Clausena lansium (Lour.) Skeels Leaves and Antifungal Activity.
10.20307/nps.2016.22.1.35
- Author:
Vu Duc NAM
1
;
Fujimatsu TERUHISA
;
Takigawa HIROFUMI
;
Kusuoku HIROSHI
;
Nguyen Minh KHOI
;
Le Viet DUNG
;
Do Thi HA
;
Hashimoto HIROSHI
Author Information
1. National Institute of Medicinal Materials, Hanoi 100000, Vietnam. khoi_nguyenminh@yahoo.co.uk
- Publication Type:Original Article
- Keywords:
Antifungal;
Clausena lansium;
Dihydroindicolactone;
Furanocoumarin
- MeSH:
Clausena*;
Ethanol;
Ficusin;
Vietnam
- From:Natural Product Sciences
2016;22(1):35-40
- CountryRepublic of Korea
- Language:English
-
Abstract:
The first study on chemical constituents and biological activities of Clausena lansium (Lour.) Skeels (Rutaceae) growing in Vietnam has been done. Phytochemical investigation of n-hexane extract led to the isolation of five compounds: dihydroindicolactone (1), 8-geranyloxy psoralen (2), imperatorin (3), heraclenol (4) and indicolactone (5), in which this is the first report on the presence of dihydroindicolactone (1). Their structures were elucidated based on LC/MS/NMR hyphenated techniques as well as comparison with those of literature data. The n-hexane extract and its subfractions, ethanol 95% extract and several isolated compounds were evaluated for antifungal activity.
