A Case of Herpes Gestationis.
- Author:
Dou Hee YOON
;
Dong Won LEE
;
Baik Kee CHO
;
Chang Woo LEE
- Publication Type:In Vitro ; Case Report
- Keywords:
Autoantibody;
Elerpes gestationis;
lmmunoblot analysis
- MeSH:
Adult;
Antibodies;
Autoantibodies;
Basement Membrane;
Diagnosis;
Female;
Humans;
Immunoglobulin G;
Korea;
Nose;
Pemphigoid Gestationis*;
Postpartum Period;
Pregnancy;
Skin Diseases
- From:Korean Journal of Dermatology
1995;33(4):727-732
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Herpes gestationis(HG) characterized by the development of autoantibodies to the basement membrane is a pruritic bullous dermatosis of pregnancy and the postpartum period. HG is diag nosed on the basis of clinical findings, and a direct or indirect immunofluorescent test including an assaying for the denmonstration of IgG autoantibody in the serum. We report a case of herpes gestationis in Korea which showed a typical clinical and histopathologic findings accuring in a 30-year old primiparous patient. We could confirm the diagnosis in this case by in vitro C3 staining, and immunoblot analysis which revealed the presence of antibodies in her sertim against 180kD antigen of epidermal protein.
