A Case of Condyloma Acuminatum Showing Malignant Transformation.
- Author:
Oong KIM
;
In Kyung KANG
;
Kyu Chul CHOI
- Publication Type:Case Report
- Keywords:
Condyloma Acuminatun;
Malignant Transformation;
Human Papillornavis 16
- MeSH:
Bowen's Disease;
Female;
Genitalia;
Human papillomavirus 16;
Humans;
Incidence;
Male;
Polymerase Chain Reaction;
Prevalence;
Uterine Cervical Neoplasms;
Warts
- From:Korean Journal of Dermatology
1995;33(4):759-763
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Condyloma acuminatum occurs in perianal and genital area by infection of human papillomavirus (HPV) and appeais as fairly soft verrucous papules or a cauliflower-like mass. So far 60 HPV types have been identified. Among them, condyloma acuminatum is predomi-nantly associated with HPV 16, 18 and rarely with 16, 18. HPV 16, 18 is regarded as a high-risk HPV infection because of the association of HPV 16, 18 with Bowens disease, cervical cancer, and anogenital cancer. In additioin, a significant appearance of cervical anaplastic lesions is preceded by condyloma acuminatum and a high prevalence of cervical dysplasia has been found in female consorts of men with geriital warts. Malignant transformation has been observed in rare incidences of condyloma acumina a on the external genitalia. We present a case of condylc ma acuminatum showing malignant transforrnation. The patient also has uterine cervical carcinonia. We detected HPV 16 in the lesion using polymerase chain reaction.
