Hyperhomocysteinemia and kidney diseases.
- Author:
Yun-Feng ZHOU
1
;
You-Fei GUAN
2
Author Information
1. Medical Research Center, Physiology Department of Basic Medical College, Shenzhen University Health Science Center, Shenzhen 518060, China.
2. Advanced Institute of Medical Sciences, Dalian Medical University, Dalian 116044, China. guanyf@dmu.edu.cn.
- Publication Type:Journal Article
- MeSH:
Homocysteine;
Humans;
Hyperhomocysteinemia;
complications;
Kidney Diseases;
complications
- From:
Acta Physiologica Sinica
2018;70(6):607-611
- CountryChina
- Language:Chinese
-
Abstract:
Homocysteine (Hcy) is an intermediate metabolite of methionine metabolism. Hyperhomocysteinemia (HHcy) is defined as a condition characterized by plasma Hcy level above 16 μmol/L which can result from abnormal Hcy metabolism. HHcy has been confirmed to be related to cardio-cerebrovascular disease, peripheral vascular disorders, neurodegenerative diseases, diabetes, pregnancy-induced hypertension syndrome, liver cirrhosis and kidney diseases. In this review, we summarize the correlation between HHcy and kidney diseases. Elucidating the role of HHcy in kidney diseases may provide a new strategy to prevent and treat kidney diseases.
