Cancer pain, a serious threat to patientsmemory.
- Author:
Xue-Yan OUYANG
1
;
Chao YANG
2
;
Zhen ZHU
3
;
Jing LI
1
;
Yun-Heng SUN
1
;
Gang DING
4
;
Yong-Hua JI
5
;
Feng JIANG
6
Author Information
1. Oncology Department, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.
2. Scientific Research Management Department, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Chongming Branch, Shanghai 202150, China.
3. Xinhua Translational Institute for Cancer Pain, Shanghai 202150, China.
4. Oncology Department, Shanghai International Medical Center, Shanghai 201318, China. gang.ding@simcgroup.com.
5. Xinhua Translational Institute for Cancer Pain, Shanghai 202150, China. yhji@staff.shu.edu.cn.
6. Scientific Research Management Department, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Chongming Branch, Shanghai 202150, China. jf365321@163.com.
- Publication Type:Journal Article
- MeSH:
Cancer Pain;
physiopathology;
Central Nervous System;
Humans;
Memory;
Neurotransmitter Agents;
Pain;
Peripheral Nerves
- From:
Acta Physiologica Sinica
2019;71(2):343-349
- CountryChina
- Language:Chinese
-
Abstract:
A large number of cancer patients suffer from pain. Growing evidence suggested that pain might be a serious risk factor for cancer patients. The shared modulators and modulation pathways between neural system and tumor cells, such as various neurotransmitters and neurogenic cytokines, provide essential basis for the effect of pain on tumor. In this article, we reviewed some possible mechanism of this process from two aspects: the systematic regulation of central nervous system on endocrine and immunity, and the regional regulation of peripheral nerves on tumor cells. The aim of this review is to provide more innovative knowledge about pain and cancer and to emphasize the importance of anti-pain in the therapy of cancer.
