The cardiovascular protection of irisin and its research progress in sports field.
- Author:
Shen WANG
1
;
Jing-Wen LIAO
2
;
Hong-Gang YIN
2
;
Hui-Hui JI
3
;
Hang YU
3
;
Yu-Hao ZOU
3
;
Min HU
4
Author Information
1. Department of Sports and Health, Guangzhou Sport University, Guangzhou 510500, China.
2. Scientific Research Center, Guangzhou Sport University, Guangzhou 510500, China.
3. Medical School of Ningbo University, Ningbo 315000, China.
4. Scientific Research Center, Guangzhou Sport University, Guangzhou 510500, China. whoomin@aliyun.com.
- Publication Type:Journal Article
- MeSH:
Cardiovascular Diseases;
prevention & control;
Diabetes Mellitus;
Exercise;
Fibronectins;
physiology;
Humans;
Muscle, Skeletal;
Sports Medicine
- From:
Acta Physiologica Sinica
2019;71(3):478-484
- CountryChina
- Language:Chinese
-
Abstract:
Irisin is a circulating myokine induced by exercise, which is a cleaved version of fibronectin type III domain containing protein 5 (FNDC5). It can promote the browning of white fat tissue, increase energy consumption, and decrease weight. Irisin plays an important role in the regulation of various diseases, such as diabetes and coronary heart disease. Different types of exercise have different effects on irisin level in blood circulation, and moderate exercise can reduce cardiovascular symptoms. In this paper, the cardiovascular protective effect of irisin and its research progress in the field of exercise are reviewed, hoping to provide a new target for the prevention and treatment of cardiovascular diseases.
