Clinical Charicteristics of Primary Lung Cancer Patients in a Tertiary Hospital.
10.4046/trd.2006.60.3.321
- Author:
Jeong Seon RYU
1
;
Hun Jae LEE
;
Jong Han LEEM
;
Lucia KIM
;
Kyung Hee LEE
;
Jae Hwa CHO
;
Young Han YOON
;
Seung Min KWAK
;
Hong Lyeol LEE
;
Kwang Ho KIM
;
John Kyu LOH
;
Soo Kyung JUNG
Author Information
1. Department of Internal Medicine, College of Medicine, Inha University, Incheon, South Korea. jsryu@inha.ac.kr
- Publication Type:Original Article
- Keywords:
Lung cancer;
Clinical characteristics;
Symptom;
Smoking
- MeSH:
Adenocarcinoma;
Body Weight;
Carcinoma, Squamous Cell;
Cardiovascular Diseases;
Diabetes Mellitus;
Diagnosis;
Female;
Humans;
Idiopathic Pulmonary Fibrosis;
Incidence;
Korea;
Lung Neoplasms*;
Lung*;
Male;
Prospective Studies;
Pulmonary Disease, Chronic Obstructive;
Surveys and Questionnaires;
Retrospective Studies;
Smoke;
Smoking;
Tertiary Care Centers*;
Tobacco Products;
Tuberculosis, Pulmonary
- From:Tuberculosis and Respiratory Diseases
2006;60(3):321-329
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: To evaluate the clinical characteristics of lung cancer patients in Korea, where there is a higher number of smokers than in Western countries. METHODS: A retrospective study was performed on 1655 lung cancer patients, who were diagnosed at a university hospital between September 1996 and August 2005. Age, gender, cell types and clinical stage were analysed. Of 941 patients, who responded to a questionnaire at the time of diagnosis, the smoking habits, occupational history, family history of lung cancer in the first-degree relatives, coexisting diseases (diabetes mellitus and cardiovascular disease), body weight loss, ECOG performance status and presenting symptoms, were examined prospectively. In addition, coexisting diseases including chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis and active pulmonary tuberculosis were evaluated. RESULTS: Of the 1655 patients, the male to females ratio was 3.6. Squamous cell carcinoma was the most common cancer whereas adenocarcinoma was more common in lifetime nonsmokers or women. 19.9% of the patients were non smokers and 80.1% ever smokers. Since 2000, there was an increase in the incidence of adenocarcinoma with a corresponding decrease in the incidence of squamous cell carcinoma. 6.2% of patients were asymptomatic. A coincident diagnosis of chronic obstructive pulmonary disease, cardiovascular disease, diabetes mellitus, active pulmonary tuberculosis, and idiopathic pulmonary fibrosis was made in: 44.1%, 22.2%, 10.7%, 3.9%, and 1.6% of patients, respectively. A positive family history of lung cancer in the first-degree relatives was identified in 4.4% of patients. An occupational history relevant to lung cancer was identified in 12.2% of patients. CONCLUSION: There is a high proportion of cigarette smokers in Korean lung cancer patients. The most common cell type was squamous cell carcinoma. However, a more detailed, prospective study of the clinical characteristics will be needed to better characterize lung cancer in Korea.
