Research advances in relationship between mitochondrial dynamics and cellular energy metabolism and exercise intervention.
- Author:
Yong-Cai ZHAO
1
;
Bing-Hong GAO
2
Author Information
1. Graduate School, Shanghai University of Sport, Shanghai 200438, China.
2. School of Physical Education and Sport Training, Shanghai University of Sport, Shanghai 200438, China. gaobinghong@126.com.
- Publication Type:Journal Article
- MeSH:
Adenosine Triphosphate;
biosynthesis;
Autophagy;
Energy Metabolism;
Exercise;
Humans;
Mitochondria;
physiology;
Mitochondrial Dynamics;
Mitochondrial Proteins;
metabolism
- From:
Acta Physiologica Sinica
2019;71(4):625-636
- CountryChina
- Language:Chinese
-
Abstract:
Mitochondrial dynamics, involving mitochondrial fusion, fission and autophagy, plays an important role in maintaining cellular physiological function and homeostasis. Mitochondria are the "energy plant" of human body, so the changes of mitochondrial fusion, division and autophagy are important for cell respiration and energy production. On the other hand, energy metabolism influences mitochondrial dynamics in turn. This paper reviewed the recent advances in studies on the relationship between energy metabolism and the proteins regulating mitochondrial fusion, fission and autophagy. The association of mitochondrial dynamics with electron chain complex expression, oxidative phosphorylation and ATP synthesis upon exercise intervention will provide theoretical references for the further studies in sports training and disease intervention.
