Research advances in relationship between biological clock and cardiovascular diseases.
- Author:
Ting-Ting JIANG
1
;
Shuang JI
1
;
Guang-Rui YANG
2
;
Li-Hong CHEN
3
Author Information
1. Advanced Institute for Medical Sciences, Dalian Medical University, Dalian 116044, China.
2. School of Bioengineering, Dalian University of Technology, Dalian 116044, China.
3. Advanced Institute for Medical Sciences, Dalian Medical University, Dalian 116044, China. bjclh2000@163.com.
- Publication Type:Journal Article
- MeSH:
Blood Pressure;
Cardiovascular Diseases;
physiopathology;
Circadian Clocks;
Circadian Rhythm;
Endothelial Cells;
cytology;
Heart Rate;
Humans;
Myocytes, Cardiac;
metabolism;
Vasoconstriction;
Vasodilation
- From:
Acta Physiologica Sinica
2019;71(5):783-791
- CountryChina
- Language:Chinese
-
Abstract:
Circadian rhythms widely exist in living organisms, and they are regulated by the biological clock. Growing evidence has shown that circadian rhythms are tightly related to the physiological function of the cardiovascular system, including blood pressure, heart rate, metabolism of cardiomyocytes, function of endothelial cells, and vasoconstriction and vasodilation. In addition, disruption of circadian rhythms has been considered as one of the important risk factors for cardiovascular diseases, such as myocardial infarction. This review summarizes the recent research advances in the relationship between circadian clock and cardiovascular diseases, hoping to improve treatment strategies for patients with cardiovascular diseases according to the theory of biological clock.
