Development of an Autism Subtyping Questionnaire Based on Social Behaviors.
10.1007/s12264-018-0224-8
- Author:
Fan-Chao MENG
1
;
Xin-Jie XU
2
;
Tian-Jia SONG
1
;
Xiao-Jing SHOU
1
;
Xiao-Li WANG
3
;
Song-Ping HAN
4
;
Ji-Sheng HAN
5
;
Rong ZHANG
6
Author Information
1. Neuroscience Research Institute, Peking University, Beijing, 100083, China.
2. Central Laboratory, Research Center for Translational Medicine, Department of Scientific Research, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100730, China.
3. Division of Maternal and Child Health, School of Public Health, Peking University Health Science Center, Beijing, 100083, China.
4. Wuxi Shenpingxintai Medical Technology Co., Ltd., Wuxi, 214000, China.
5. Neuroscience Research Institute, Peking University, Beijing, 100083, China. hanjisheng@bjmu.edu.cn.
6. Neuroscience Research Institute, Peking University, Beijing, 100083, China. zhangrong@bjmu.edu.cn.
- Publication Type:Journal Article
- Keywords:
Autism spectrum disorder;
Beijing Autism Subtyping Questionnaire;
Subtypes;
Wing Subgroups Questionnaire
- MeSH:
Autism Spectrum Disorder;
diagnosis;
Child, Preschool;
Factor Analysis, Statistical;
Female;
Humans;
Male;
Reproducibility of Results;
Social Behavior;
Surveys and Questionnaires;
Translating
- From:Neuroscience Bulletin
2018;34(5):789-800
- CountryChina
- Language:English
-
Abstract:
Autism spectrum disorder can be differentiated into three subtypes (aloof, passive, and active-but-odd) based on social behaviors according to the Wing Subgroups Questionnaire (WSQ). However, the correlations between the scores on some individual items and the total score are poor. In the present study, we translated the WSQ into Chinese, modified it, validated it in autistic and typically-developing Chinese children, and renamed it the Beijing Autism Subtyping Questionnaire (BASQ). Our results demonstrated that the BASQ had improved validity and reliability, and differentiated autistic children into these three subtypes more precisely. We noted that the autistic symptoms tended to be severe in the aloof, moderate in the passive, and mild in the active-but-odd subtypes. The modified questionnaire may facilitate etiological studies and the selection of therapeutic regimes.
