Danshen: a phytochemical and pharmacological overview.
10.1016/S1875-5364(19)30010-X
- Author:
Xiao-Dan MEIM
1
;
Yan-Feng CAO
1
;
Yan-Yun CHE
2
;
Jing LI
3
;
Zhan-Peng SHANG
1
;
Wen-Jing ZHAO
1
;
Yan-Jiang QIAO
4
;
Jia-Yu ZHANG
5
Author Information
1. School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 102488, China.
2. College of Pharmaceutical Science, Yunnan University of Traditional Chinese Medicine, Kunming 650500, China.
3. College of Basic Medicine, Jinzhou Medical University, Jinzhou 121001, China.
4. School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 102488, China. Electronic address: yjqiao@263.Net.
5. Beijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China. Electronic address: zhangjiayu0615@163.com.
- Publication Type:Journal Article
- Keywords:
Chemical constituents;
Danshen;
Pharmacological activities;
Quality control;
Traditional uses
- MeSH:
Diterpenes;
chemistry;
Drugs, Chinese Herbal;
chemistry;
isolation & purification;
pharmacology;
therapeutic use;
Hydroxybenzoates;
chemistry;
Molecular Structure;
Oils, Volatile;
chemistry;
Phytochemicals;
chemistry;
isolation & purification;
pharmacology;
therapeutic use;
Plant Roots;
chemistry;
Quality Control;
Salvia miltiorrhiza;
chemistry
- From:
Chinese Journal of Natural Medicines (English Ed.)
2019;17(1):59-80
- CountryChina
- Language:English
-
Abstract:
Danshen, the dried root or rhizome of Salvia miltiorrhiza Bge., is a traditional and folk medicine in Asian countries, especially in China and Japan. In this review, we summarized the recent researches of Danshen in traditional uses and preparations, chemical constituents, pharmacological activities and side effects. A total of 201 compounds from Danshen have been reported, including lipophilic diterpenoids, water-soluble phenolic acids, and other constituents, which have showed various pharmacological activities, such as anti-inflammation, anti-oxidation, anti-tumor, anti-atherogenesis, and anti-diabetes. This article intends to provide novel insight information for further development of Danshen, which could be of great value to its improvement of utilization.
