Histopathologic Study of Erythema Nodosum: Licke Lesions in Behcet's Disease.
- Author:
Kwang Hyun CHO
;
Kye Yong SONG
;
Mi Kyung CHO
;
Yoo Shin LEE
;
Eui Keun HAM
- Publication Type:Original Article
- MeSH:
Blood Vessels;
Dermis;
Erythema Nodosum*;
Erythema*;
Granuloma;
Humans;
Neutrophil Infiltration;
Subcutaneous Tissue;
Sweat Glands;
Thrombophlebitis;
Vasculitis
- From:Korean Journal of Dermatology
1988;26(3):330-337
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A histopathological study of erythema nodosum-like lesions in Behcet's disease was performed on 55 patients with incomplete and suspect types of Behcet's disease. Relatively common characteristics in histopathology of erythema nodosum-like lesions could be found in the patients with incomplete type of Behcet's disease. The histopathologic findings of erythema nodosum-like lesions in 21 patients with incomplete type of Behcet's disease were as follows : l. A moderate lymphocytic infiltration was found around the blood vessels and the sweat glands in the dermis. In the subcutaneous tissue, besides lymphohistiocytic infiltration, neutrophils were present in significant number in 9 cases (42.9%) 2. Vasculitis of small vessels was found within the periphery of fat lobules in 7 cases (81.0%), Five cases (23.8%) also showed thrombophlebitis. Seven cases (33.3%) showed histiocytic granuloma formation within the fat lobules. Microabscess formation in the subcutaneous tissue was seen in 5 cases (23.8 %), but it was not certain whether this was the charateristic feature.