Research progress on metabolism and pharmacological activities of several iridoid glycosides.
10.19540/j.cnki.cjcmm.20171106.004
- Author:
Chang-Song XUE
1
;
Jing XU
1
;
Cui-Ping LI
1
;
Yu WANG
2
;
Mei-Chen LIU
2
;
Guang-Qing XIA
2
Author Information
1. Changbai Mountain Edible Plant Resource Development Engineering Center of Jilin Province, Tonghua Normal University, Tonghua 134002, China.
2. Key Lab of Changbai Mountain Plant Germplasm Resources Protection and Utilization Jilin Province, Tonghua Normal University, Tonghua 134000, China.
- Publication Type:Journal Article
- Keywords:
iridoid glycoside;
metabolites;
pharmacological activities
- MeSH:
Drugs, Chinese Herbal;
metabolism;
pharmacology;
Humans;
Iridoid Glycosides;
metabolism;
pharmacology
- From:
China Journal of Chinese Materia Medica
2018;43(1):39-45
- CountryChina
- Language:Chinese
-
Abstract:
As a large category of natural products widely present in traditional Chinese medicine, iridoid glycosides have multiple pharmacological activities. Recent researches suggest that iridoid glycosides mainly exist in the forms of original form, aglycone and a series of their Ⅰ and Ⅱ metabolites under the biotransformation effect, and their metabolites have been proved to have multiple pharmacological activities. The research progress on metabolism and metabolite activities of several iridoid glycosides would be reviewed in this article, to provide a theoretical basis for the further development and utilization of iridoid compounds and their metabolites.