Quantitative analysis and stability of -hydroxybenzyl hydrogen sulfite in sulfur-fumigated Gastrodiae Rhizoma.
10.19540/j.cnki.cjcmm.20171023.003
- Author:
Chuan-Zhi KANG
1
;
Jing-Yi JIANG
1
;
Wan-Zhen YANG
1
;
Li ZHOU
1
;
Chao-Geng LV
1
;
Jia-Xing LI
1
;
Sheng WANG
1
;
Tao ZHOU
2
;
Ye YANG
3
;
Lu-Qi HUANG
1
;
Lan-Ping GUO
1
Author Information
1. State Key Laboratory and Breeding Base of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
2. Guiyang College of Traditional Chinese Medicine, Guiyang 550025, China.
3. Kunming University of Science and Technology, Kunming 650093, China.
- Publication Type:Journal Article
- Keywords:
Gastrodiae Rhizoma;
UPLC-MS/MS;
chemical marker of sulfur fumigation;
quality evaluation;
stability
- MeSH:
China;
Chromatography, Liquid;
Drugs, Chinese Herbal;
chemistry;
standards;
Fumigation;
Gastrodia;
chemistry;
Quality Control;
Rhizome;
chemistry;
Sulfites;
analysis;
Sulfur;
Tandem Mass Spectrometry
- From:
China Journal of Chinese Materia Medica
2018;43(2):248-253
- CountryChina
- Language:Chinese
-
Abstract:
Studies on the characteristic chemical markers of sulfur fumigation have become an effective auxiliary way for quality control of traditional Chinese medicine. This study established a quantitative analysis method for the determination of -hydroxybenzyl hydrogen sulfite (-HS) in Gastrodiae Rhizoma (GR) based on UPLC-MS/MS. Then, 37 batches of GR were screened, and the results showed that 27 batches of them were sulfur-fumigated. Especially, the GR samples in Yunnan producing areas were sulfur-fumigated more seriously. Based on the stability of -HS after different storage time and heat treatment methods, it was found that the content of -HS was stable and reliable in the storage period of 8 months and under normal heat treatment (50, 60, 70, 80 °C) conditions. In conclusion, this study shows a high sensitivity, good selectivity and good stability of -HS, which can provide reference for the quality control and sulfur fumigation screening of GR.
