Effect on sperm quality of asthenospermia and oligospermia treated with grain-moxibustion combined with medicine therapy.
10.13703/j.0255-2930.2019.08.012
- Author:
Yan-Yun MU
1
;
Qi-Xin HUA
2
;
Bing YAO
3
;
Yu-Ming FENG
3
;
Zheng-Yun XIE
4
;
Zhao GAO
5
;
Wen-Jing ZHANG
6
;
You-Bing XIA
7
Author Information
1. Second Clinical Medical College, Nanjing University of CM, Nanjing 210023, Jiangsu Province, China.
2. Department of Acupuncture and Moxibustion, Nanjing Hospital of TCM.
3. Reproductive Center, General Hospital of Eastern Military Command of PLA.
4. Preventive Treatment Center, Nanjing Hospital of TCM.
5. Pain Management, Zhongda Hospital Affiliated to Southestern University.
6. Department of Outpatient, Beijing Haidian Garrison Command Fifth Retired Cadre Sanatorium.
7. Affiliated Hospital of Xuzhou Medical University.
- Publication Type:Journal Article
- Keywords:
asthenospermia and oligospermia;
grain-moxibustion;
sperm DNA fragmentation index (DFI);
sperm concentration;
sperm progressive motility
- MeSH:
Humans;
Male;
Medicine, Chinese Traditional;
Moxibustion;
Oligospermia;
therapy;
Sperm Count;
Sperm Motility;
Spermatozoa
- From:
Chinese Acupuncture & Moxibustion
2019;39(8):843-848
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the clinical effect of grain-moxibustion combined with medicine therapy for asthenospermia and oligospermia.
METHODS:A tatal of 60 patients were randomized into an observation group (30 cases) and a control group (30 cases) according to 1︰1 ratio. In the control group, vitamin E capsules were taken orally one capsule each time, twice a day, and pills 6 g each time, three times a day for a total of 3 months. In the observation group, grain-moxibustion was applied at Guanyuan (CV 4)，Shenshu (BL 23) and Zusanli (ST 36) based on the control group, once a week for 3 months, with a total of 12 times. The sperm concentration and sperm progressive motility were measured by automatic sperm quality analysis system in the two groups, and the clinical effects were compared. Sperm DNA fragmentation index (DFI) in the observation group was measured by sperm nucleus chromosome structure assay (SCSA).
RESULTS:①The sperm concentrations and sperm progressive motilities after 1-month, 2-month and 3-month of treatment were increased compared with those before treatment in the two groups (<0.01), and they were increased with time. In the two groups, 2-month and 1-month of treatment, 3-month and 2-month of treatment were compared, the sperm concentrations and sperm progressive motilities were significantly increased (<0.01). The sperm concentrations after 1-month, 2-month and 3-month of treatment in the observation group were higher than those in the control group (<0.01), the sperm progressive motility after 3-month of treatment in the observation group was higher than that in the control group (<0.05). ②After 3-month of treatment，the DFI in the observation group was significantly reduced compared with that before treatment (<0.01). ③The total effective rate in the observation group after 3-month of treatment was 86.7% (26/30), which was superior to 63.3% (19/30) in the control group (<0.05).
CONCLUSION:Grain-moxibustion combined with medicine therapy can improve sperm concentration and sperm progressive motility, enhance the integrity of sperm DNA.
