Leiomyosarcoma of the Great Saphenous Vein:Report of One Case and Meta-analysis.
10.3881/j.issn.1000-503X.10738
- Author:
Xiang ZHANG
1
;
Ya Hong WANG
2
;
Yue Xin CHEN
3
;
Bao LIU
3
;
Yue Hong ZHENG
3
Author Information
1. Department of General Surgery, PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
2. Department of Ultrasound, PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
3. Department of Vascular Surgery,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
- Publication Type:Case Reports
- MeSH:
Female;
Humans;
Leiomyosarcoma;
pathology;
Male;
Middle Aged;
Neoplasm Recurrence, Local;
Saphenous Vein;
pathology;
Survival Rate
- From:
Acta Academiae Medicinae Sinicae
2019;41(3):435-442
- CountryChina
- Language:Chinese
-
Abstract:
Leiomyosarcoma(LMS)of the great saphenous vein(GSV)is a rare condition that is often misdiagnosed due to the lack of typical clinical manifestations.This article reported a GSV-LMS case diagnosed and treated in Peking Union Medical College Hospital.Meta-analysis of the current case and 41 cases derived from CNKI,WANFANG DATA,and MEDLINE database was also conducted,which revealed that the male to female ratio of GSV-LMS was 11:10;the median age of disease onset was 59.5 years;the most commonly affected region was thigh.Due to lack of specific clinical features,42.9% of GSV-LMS patients were misdiagnosed at presentation.Radical resection is the most effective therapy,and the indications,effectiveness and protocols of adjuvant radiochemotherapy remain unclear.The 3-and 5-year overall survival rate was 86.1% and 77.5%,respectively.Recurrence and metastasis occurred in 31.0% of patients after surgery.
