Meta Analysis of Risks of Cardiocerebral Vascular Events in Patients with Primary Biliary Cholangitis.
10.3881/j.issn.1000-503X.10637
- Author:
Xi XIE
1
;
Sheng TANG
2
;
Jia WANG
1
;
Jin Wei CHEN
1
;
Jing TIAN
1
;
Ni MAO
1
;
Yi Ming LIU
1
;
Fen LI
1
Author Information
1. Department of Rheumatology,the Second Xiangya Hospital of Central South University,Changsha 410011,China.
2. Department of Internal Medicine,Yongzhou Hospital of Traditional Chinese Medicine,Yongzhou,Hunan 425000,China.
- Publication Type:Journal Article
- MeSH:
Carotid Stenosis;
etiology;
Cholangitis;
complications;
Coronary Disease;
etiology;
Humans;
Ischemic Attack, Transient;
etiology;
Liver Cirrhosis, Biliary;
complications;
Risk Factors;
Stroke;
etiology
- From:
Acta Academiae Medicinae Sinicae
2019;41(4):457-463
- CountryChina
- Language:Chinese
-
Abstract:
To systematically evaluate the risks of cardiocerebral vascular events in patients with primary biliary cholangitis(PBC). Methods We carried out a Meta analysis by RevMan 5.3 software to investigate literatureon the risk of cardiocerebral vascular events in patients with PBC and controls. Results Compared with non-PBC controls,PBC patients had significantly higher risk of coronary events(=1.56,=0.0002);however,the risk of cerebrovascular events showed no significant difference between these two groups(=1.01,=0.94).Subgroup analysis demonstrated a significantly lower risk of transient ischemic attack or carotid stenosis in PBC patients(=0.63,=0.03);however,there was no significant difference in the risk of stroke(=1.11,=0.40). Conclusion Patients with PBC have an increased risk of coronary events but may have a lower risk of transient ischemic attack or carotid stenosis.
