Leucine-rich Glioma-inactivated Protein 1 Antibody-associated Encephalitis:Report of Two Cases.
10.3881/j.issn.1000-503X.11197
- Author:
Jun Jie ZHAO
1
;
Yan Hong YANG
1
Author Information
1. Department of Neurology,Jinan People's Hospital of Shandong Province,Jinan 271100,China.
- Publication Type:Case Reports
- Keywords:
facial-arm dystonia;
leucine-rich glioma inactivation 1 protein;
limbic encephalitis;
magnetic resonance imaging
- MeSH:
Autoantibodies;
immunology;
Encephalitis;
diagnosis;
therapy;
Humans;
Proteins;
immunology
- From:
Acta Academiae Medicinae Sinicae
2019;41(5):714-718
- CountryChina
- Language:Chinese
-
Abstract:
Leucine-rich glioma-inactivated protein 1(LGI1)antibody-associated encephalitis is an autoimmune brain disease mainly seen in mid-aged and elderly people.Its main clinical manifestations include abnormal mental behaviors,facial-arm dystonia,hyponatremia,and hypokalemia.Immunotherapy with gamma globulin and/or hormone is effective.Two patients with LGT1 antibody-associated encephalitis were diagnosed in our center between January 2018 and October 2018,with typical clinical findings.The disease was cursed after immunoglobulin and hormone treatments.
