Efficacy of electroacupuncture nerve stimulation therapy for interstitial cystitis/bladder pain syndrome.
10.13703/j.0255-2930.2019.05.003
- Author:
Ting-Ting LV
1
,
2
;
Jian-Wei LV
3
;
Si-You WANG
4
;
Chen JIANG
3
;
Yin-Jun GU
3
;
Hui-Rong LIU
4
Author Information
1. Shanghai University of TCM, Shanghai 201203, China
2. South Campus of Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200112.
3. South Campus of Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200112.
4. Shanghai University of TCM, Shanghai 201203, China.
- Publication Type:Journal Article
- Keywords:
bladder perfusion;
electroacupuncture nerve stimulation therapy (ENST);
interstitial cystitis/painful bladder syndrome (IC/PBS)
- MeSH:
Cystitis, Interstitial;
therapy;
Electroacupuncture;
Humans;
Pain;
Pain Management;
Treatment Outcome;
Urinary Bladder Diseases;
therapy
- From:
Chinese Acupuncture & Moxibustion
2019;39(5):467-472
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To explore the clinical efficacy of electroacupuncture nerve stimulation therapy (ENST) for interstitial cystitis/painful bladder syndrome (IC/PBS).
METHODS:A total of 68 patients with IC/PBS were randomly divided into an observation group and a control group, 34 cases in each one. The patients in the observation group were treated with ENST; abdominal four acupoints and sacral four acupoints were connected with a pair of electrodes and treated alternately every other day. The ENST was given 50 min per times, three times a week for 3 months. The patients in the control group were treated with perfusion therapy of four-medication combination (heparin sodinm, lidocaine, sodium bicarbonate, gentamicin sulfate), twice a week for the first 6-8 weeks, followed by twice per month for 3 months. The infusion fluid remained for 1 h before discharging. The O' Leary-Sant score, including interstitial cystitis symptom index (ICSI) and interstitial cystitis problem index (ICPI), 24 h urination frequency, visual analogue scale (VAS) and maximum bladder volume were observed before treatment and treatment of 1 month, 3 months and 6 months after treatment respectively; the adverse events during the treatment were also recorded.
RESULTS:Compared before treatment, the O'Leary-Sant score (ICSI, ICPI), 24 h urination frequency, VAS and maximum bladder volume in the two groups were improved after 1, 3 months treatment and 6 months after treatment (all <0.05). The scores of ICSI, ICPI, VAS and 24 h urination frequency in the observation group were significantly lower than those in the control group (<0.05). The maximum bladder volume in the observation group was significantly higher than that in the control group (<0.05). Six months after treatment, the total effective rate in the observation group was 87.5% (28/32), which was higher than 69.7% (23/33) in the control group (<0.01). No significant adverse events occurred during the treatment.
CONCLUSION:ENST could effectively relieve the clinical symptoms of IC/PBS, but its long-term efficacy needs further observation.
