Significance of Peripheral Blood Lymphatic to Monocyte Ratio in the Progress of PGI-DLBCL.
10.19746/j.cnki.issn.1009-2137.2019.04.020
- Author:
Ke-Meng SUN
1
;
Wei SANG
1
;
Lin-Yan XU
2
;
Dong-Mei YAN
1
;
Xu-Guang SONG
1
;
Cai SUN
1
;
Xiao-Kun SUN
2
;
Kai-Lin XU
3
Author Information
1. Department of Hematology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, Jiangsu Province, China.
2. Institute of Hematology,Xuzhou Medical University, Xuzhou 221002, Jiangsu Province, China.
3. Department of Hematology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, Jiangsu Province, China,Institute of Hematology,Xuzhou Medical University, Xuzhou 221002, Jiangsu Province, China,E-mail:lihmd@163.com.
- Publication Type:Journal Article
- MeSH:
Humans;
Leukocyte Count;
Lymphocytes;
Lymphoma, Large B-Cell, Diffuse;
Monocytes;
Prognosis;
Retrospective Studies
- From:
Journal of Experimental Hematology
2019;27(4):1118-1122
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To explore the significance of lymphocyte to monocyte ratio (LMR) in the disease progress of primary gastrointestinal diffuse large B-cell lymphoma (PGI-DLBCL).
METHODS:The clinical data of 43 patients diagnosed as PGI-DLBCL in our hospital from January 2011 to December 2015 were collected, and the disease progress was followed up.
RESULTS:According to the ROC curve, the threshold value of LMR for 2 years PFS (%) of PGI-DLBCL patients was 2.6. Unvariate analysis showed that LMR (P＜0.05), large enclosed mass lesion (P＜0.01) and IPI (P＜0.05) were prognostic factors affecting PFS, the COX regression model multivariate analysis showed that LMR＜2.6 [ (risk ratio (RR)=3.083, 95%CI 1.828-8.313, P＜0.01], and large enclosed mass lesions (RR=2.718, 95%CI 1.339-6.424, P＜0.05) were the independent adverse prognostic factor for two years PFS.
CONCLUSION:Both LMR＜2.6 and large enclosed mass lesions relate with the progress of PGI-DLBCL.
